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PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix OOC

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Consumables

Multi-chip plates
3D validated cells
NASH-in-a-box
Bioavailability assay kit: Human 18
DILI assay kit: Human 24
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Search

8th May 2025

Why the FDA animal testing phase-out for monoclonal antibodies?

8th May 2025

Microphysiological systems for mAbs development: how do they address animal limitations?

1st May 2025
Blog

Microphysiological systems for mAbs development: how do they address animal limitations?

1st May 2025
Blog

Why the FDA animal testing phase-out for monoclonal antibodies?

29th April 2025
Press releases

NIH to prioritize human-based research technologies & reduce animal use in research

24th April 2025

How OOC can improve in vitro to in vivo translatability of preclinical data

24th April 2025
Press releases

CN Bio and Pharmaron establish long-term strategic partnership to develop OOC technologies on a global R&D platform

10th April 2025

Developments in Drug Discovery

10th April 2025

Organ-on-a-chip: a modernized toolbox for drug discovery challenges

10th April 2025

PhysioMimix® bioavailability assay kit: Human 18 for simultaneous oral and intravenous in vitro bioavailability profiling

10th April 2025

PhysioMimix® DILI assay kit: Human 24 for deeper mechanistic hepatotoxicity insights

10th April 2025
Press releases

FDA’s plan to phase out animal testing requirement for monoclonal antibodies and other drugs with more human-relevant methods

7th April 2025

Advancing oligonucleotide therapies with liver-on-a-chip models

4th April 2025

A liver microphysiological system to study the delivery and efficacy of oligonucleotide-based therapeutics

27th March 2025

Harnessing liver-on-a-chip models for drug safety

27th March 2025

Advancing oligonucleotide therapies with liver-on-a-chip models

19th March 2025

Oligonucleotide delivery

13th March 2025

Addressing the challenges of developing new modality drugs

11th March 2025

Sign up for our newsletter

6th March 2025

Multimodal imaging of a liver-on-a-chip model using labelled and label-free optical microscopy techniques

28th February 2025

Validating a human dual-organ MPS for better drug (ADME) studies

27th February 2025

The Rise of Oligonucleotide Therapeutics: Overcoming ADMET Development Challenges with Human-Centric Approaches

26th February 2025

How Organ-on-a-chip can reduce DILI risk in drug development

25th February 2025

Evaluating a human DILI assay kit’s ability to unlock complex mechanisms of toxicity

24th February 2025
Blog

The Rise of Oligonucleotide Therapeutics: Overcoming ADMET Development Challenges with Human-Centric Approaches

4th February 2025

PhysioMimix® DILI Assay Kit

4th February 2025
Press releases

CN Bio launches PhysioMimix® DILI assay kit: Human 24

30th January 2025

Countdown

13th January 2025
Press releases

CN Bio signs strategic partnership with Primetech Corporation to establish distribution channel for OOC solutions in Japan

17th December 2024

MPS World Summit 2025

16th December 2024

Vox Pop Pharma – companies keen to find alternatives to animal testing – read their views

16th December 2024

Next Generation Drug Discovery: Bridging the Gap with Organ-on-a-Chip Technology

12th December 2024

Distributor support & maintenance

12th December 2024

Your PhysioMimix support packages

10th December 2024

A Gut/Liver microphysiological system for profiling human oral bioavailability

5th December 2024

WORD+ 2025

29th November 2024
Blog

Evaluating Caco-2 cell’s gold-standard status in absorption, permeability and bioavailability Studies: Are Their Limitations Justified?

29th November 2024

Evaluating Caco-2 cell’s gold-standard status in absorption, permeability and bioavailability Studies: Are Their Limitations Justified?

19th November 2024

Go/No-Go

18th November 2024
Team Q&A

Meet the CN Bio team – Oliver Culley

14th November 2024
Press releases

CN Bio launches PhysioMimix Bioavailability assay kit: Human 18

12th November 2024

A Gut/Liver microphysiological system for profiling human oral bioavailability

5th November 2024

PhysioMimix® Bioavailability Assay Kit

18th October 2024

User Group Meeting 2024 – Recap

18th October 2024
Blog

User Group Meeting 2024 – Recap

17th October 2024

Organ-on-a-chip technology

9th October 2024

Go/No-Go

8th October 2024

ACT 2024

4th October 2024

Lost in Translation

26th September 2024

Drug Discovery 2024

6th September 2024

Lost in Translation

23rd August 2024
Team Q&A

Meet the CN Bio team – Uranbileg Myagmarsuren

14th August 2024

Bridging the gap

24th July 2024

6 Challenges in ADME Drug Development

24th July 2024
Blog

6 Challenges in ADME Drug Development

24th July 2024

Organ-on-a-Chip: Big Questions Surrounding Regulation and the Roadmap to Broad Adoption

23rd July 2024

Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs

10th July 2024

SOT 2025

10th July 2024
Team Q&A

Meet the CN Bio team – Joanna Michalowska

3rd July 2024

Defining validation criteria for a primary jejunum and primary hepatocyte dual-organ MPS

2nd July 2024

How in vitro human Gut/Liver models increase confidence in ADME estimations before human trials

2nd July 2024

Organ-on-a-chip adoption: The roadmap to broader use

28th June 2024
Blog

How in vitro human Gut/Liver models increase confidence in ADME estimations before human trials

28th June 2024
Blog

Organ-on-a-chip adoption: The roadmap to broader use

28th June 2024

Developed the model, built the assay, now a focus on THROUGHPUT! The Liver-48, designed for industry adoption

27th June 2024
Press releases

CN Bio appoints Lydia Seymour as VP People and Culture to further strengthen leadership team

21st June 2024

Search

17th June 2024

How Organ-on-a-Chip Addresses R&D Challenges

13th June 2024

Developing a translational biomarker panel for use in pre-clinical advanced in vitro studies of Non-alcoholic steatohepatitis

13th June 2024
Blog

Global Fatty Liver Day 2024: How Organ-on-a-Chip Addresses R&D Challenges

10th June 2024

DMDG 2024

7th June 2024
Team Q&A
Blog

Meet the CN Bio team -Dr. Dharaminder Singh

22nd May 2024

About us – draft

7th May 2024

Careers Fair

30th April 2024

Understanding the mechanism of toxicity: OOC’s crucial role

23rd April 2024
Press releases

CN Bio raises $21 million USD in first close of Series B investment round

19th April 2024
Blog

Understanding the mechanism of toxicity: OOC’s crucial role

16th April 2024

User Group Meeting 2024

15th April 2024
Press releases

CN Bio selected for NC3R’s SensOoChip Challenge to develop advanced Heart-on-a-Chip

20th March 2024

Lab Essentials Competition

15th March 2024

EUROTOX 2024

14th March 2024

ESTIV 2024

26th February 2024

Connecting the gut and liver

20th February 2024

SOT 2024

30th January 2024
Press releases

CN Bio appoints Joseph Parisi as US Director of Sales

23rd January 2024
Press releases

CN Bio and Altis Biosystems partnership

18th January 2024

Connecting the human intestine and liver

18th January 2024

MPS World Summit 2024

11th January 2024

Gut/Liver-on-a-chip

8th January 2024

Harnessing Microphysiological Systems to Bring Humanized Processes to ADME and Bioavailability Studies

11th December 2023

Careers

6th December 2023

CONTACT FORM TEST

4th December 2023
Press releases

PhysioMimix data supports Inipharm’s INI-822 for metabolic liver disease treatment

29th November 2023

Beyond hepatotoxicity red flags

28th November 2023

Set yourself up for success with organ-on-a-chip

28th November 2023

Normalization of organ-on-a-chip samples

23rd November 2023
Press releases

OBN Awards 2023 winner!

2nd November 2023

PhysioMimix Nash-in-a-box brochure

2nd November 2023
Press releases

CN Bio appoints Neil Rumbelow as Director of Product Development

19th October 2023
Business

CN Bio showcased in PwC UK’s ‘Life Sciences Future 50’ report 2023

10th October 2023

Taking organoids to the next level

5th October 2023
Blog

Taking organoids to the next level

7th September 2023

A guide to pre-validating cells for use in Organ-on-a-chip assays

5th September 2023
Blog

A guide to pre-validating primary cells for use in Organ-on-a-chip assays

5th September 2023
Press releases

CN Bio and LifeNet Health LifeSciences partner to supply validated primary human cells for microphysiological systems

30th August 2023
Press releases

CN Bio appoints Dr. Tomasz Kostrzewski as Chief Scientific Officer

26th July 2023

Recreating Life in the Lab: How Predictive Human Organ Models are Transforming the Efficiency of Drug Discovery

26th July 2023

Tech Blast | Organ-on-a-chip technologies

17th July 2023

Summary report: Insights into new preclinical non animal models

17th July 2023

Full report: Insights into new preclinical non animal models

17th July 2023

What is organ-on-a-chip technology?

17th July 2023

Top tips for integrating organ-on-a-chip technology into your workflow

20th June 2023

Alveolar and Bronchial Microphysiological Systems for respiratory infection research and therapeutics evaluation

20th June 2023

Organ-on-a-chip Contract Research Services Brochure

9th June 2023

A primary jejunum and primary hepatocyte multi-organ MPS

6th June 2023
Press releases

CN Bio appoints Dr. Samantha Macro as Chief Financial Officer

25th May 2023

Product Recycling

3rd May 2023

Advanced pathophysiology mimicking lung models for accelerated drug discovery

3rd May 2023

Characterization of the effect of primary human hepatocytes (PHH) lots of functions in CN Bio Innovations Liver-Chip using acetaminophen

20th March 2023

Immune-mediated DILI – Predicting the unpredictable!

16th March 2023
Blog

Immune-mediated DILI – Predicting the unpredictable!

14th March 2023
Press releases

CN Bio appoints Deepak Singh as Vice President of Sales and Marketing

27th February 2023

Introducing PhysioMimix HT

27th February 2023

PhysioMimix Organ-on-a-Chip Brochure

27th February 2023

PhysioMimix Single-organ HT system

27th February 2023
Press releases

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

17th February 2023

Organ-on-a-chip provides preclinical safety toxicologists with the tools to combat drug attrition

10th February 2023

Organ-on-a-chip models in drug development

2nd February 2023

In Vitro Non-Alcoholic Steatohepatitis (NASH) Services

27th January 2023

PhysioMimix® Liver plates

27th January 2023

PhysioMimix® Multi-chip plates

27th January 2023

PhysioMimix® OOC Microphysiological Systems

17th January 2023

About CN Bio…

17th January 2023
Press releases

The FDA further expands collaboration with CN Bio to evaluate the PhysioMimix Multi-organ microphysiological system

11th January 2023

The U.S. FDA Modernization Act 2.0. Now the animal testing mandate is removed, what can be embraced in its place?

9th January 2023
Blog

The U.S. FDA Modernization Act 2.0. Now the animal testing mandate is removed, learn what can be embraced in its place.

4th January 2023

Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay

19th December 2022
Press releases

CN Bio appoints Dr Paul Brooks as Chief Executive Officer

3rd December 2022

Modelling the intestine-liver axis: The role of FXR agonists in a multi-organ microphysiological system model of non-alcoholic fatty liver disease

28th November 2022

The Human Touch

28th November 2022

ADME Studies: Determining Promising Drug Compounds

31st October 2022

The Dash for NASH

21st October 2022

How to Keep Breathing – The Future of Inhaled Medication Testing

21st October 2022

PhysioMimix Multi-organ System Animation

30th September 2022

Evaluation of in vitro human alveolar and bronchial microphysiological systems to predict the permeability and absorption of inhaled pulmonary medications

10th September 2022

Human liver microphysiological system for predicting the drug-induced liver toxicity of differing drug modalities

9th September 2022

Microphysiological system for studying fatty liver disease and its impact on drug-induced liver injury

30th August 2022

Accessibility

30th August 2022

Cookie policy

15th August 2022

Application of a gut–liver-on-a-chip device and mechanistic modeling to the quantitative in vitro pharmacokinetic study of mycophenolate mofetil

15th August 2022

Leadership team

4th August 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

25th July 2022

Pros and cons of preclinical models of Non-Alcoholic Steatohepatitis

25th July 2022

In Focus: Modeling NASH disease – organ-on-a-chip technologies

25th July 2022

Every Breath You Take

25th July 2022

Organ-on-a-Chip Models of Fatty Liver Disease

19th July 2022
Press releases

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

5th July 2022

PhysioMimix® multi-chip plates

27th June 2022

MPS World Summit Round-up

27th June 2022
Blog

MPS World Summit round-up 2022

15th June 2022

Biotechnology: Bringing New Treatments to Market

14th June 2022

Drug Discoveries Without Animal Testing

6th June 2022

Why two organs are better than one

6th June 2022

Alveolar and bronchial human microphysiological systems for use in respiratory infection research and therapeutics evaluation

6th June 2022

Primary vs. Stem-Like Cells in 3D Cultures

25th May 2022

A Breath of Fresh Air

24th May 2022
Press releases

CN Bio appoints Dr Paul Brooks as Chief Business Officer

11th May 2022

Normalization of organ-on-a-chip samples for mass spectrometry based proteomics and metabolomics via dansylation-based assay

6th May 2022

Harnessing the power of multimodal imaging to explore ASO distribution in cells, complex in vitro models and tissue

5th May 2022

PhysioMimix® NASH-in-a-box

26th April 2022
Press releases

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

6th April 2022

Careers in Biotech

24th March 2022

Terms and Conditions

24th March 2022

Regulatory

23rd March 2022

The lung in crisis

23rd March 2022
Blog

The lung in crisis: fighting back against pathogens, infections and inflammation with predictive in vitro lung models that accelerate drug discovery

17th March 2022

Lung-on-a-chip

5th March 2022

Animal Models and Microfluidic Tools with a Human Touch

5th March 2022

New Model Will Support Drug Discovery for Liver Disease NASH

1st March 2022

CN is believing

25th February 2022

Opinionated Science: What is Body-on-a-Chip Technology

24th February 2022

Debunking the 9 Myths of Organ-on-a-Chip Technology

24th February 2022
Blog

Debunking the 9 myths of Organ-on-a-chip technology

6th February 2022

Assessing drug-induced liver injury using a sensitive and selective human liver microphysiological system and clinical biomarkers

31st January 2022

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

25th January 2022

Exploration and Application of a Liver-on-a-Chip Device in Combination with Modelling and Simulation for Quantitative Drug Metabolism Studies

1st January 2022

ORGAN-ON-A-CHIP – A Novel Way to Accurately Test Delivery of Non-Standard Formulations

1st January 2022

A pressing Need for Accurate Preclinical Models of Metabolic Disease

18th December 2021

Multiorgan microphysiological systems as tools to interrogate interorgan crosstalk and complex diseases

15th December 2021

β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development

13th December 2021

Predicting Drug Bioavailability with the Modern-Day Toolkit

7th December 2021

De-risking drug-induced liver injury through the predictive power of organ-on-a-chip

7th December 2021

Improved prediction of oral bioavailability using a gut-liver microphysiological system

7th December 2021
Blog

De-risking drug-induced liver injury through the predictive power of organ-on-a-chip

1st December 2021

Reduce, Refine… Replace?

1st December 2021
Press releases

PhysioMimix® Multi-Organ Microphysiological System selected by The Scientist as a ‘Top 10 Innovation 2021′

22nd November 2021

From Dose to Circulation: Determination of Drug Oral Bioavailability Using a Gut-Liver Microphysiological System

10th November 2021
Blog

De-risking pre-clinical drug-induced liver injury with organ-on-a-chip

9th November 2021
Press releases

CN Bio and iiCON announce COVID-19 research collaboration

6th November 2021

Drug metabolism in a gut-liver microphysiological system

30th October 2021

Hype or hope – microphysiological systems?

9th October 2021

Fighting Toxic Chemicals: Evaluating the Safety of Cobinamide as a Neutralizing Agent

5th October 2021
Press releases

CN Bio expands service offering to support oncology drug discovery

22nd September 2021

Making a difference with disruptive organ-on-a-chip technology

15th September 2021

Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

9th September 2021

Predictive DILI Models: Human Liver Microphysiological System for Studying Acute and Chronic Drug-Induced Liver Toxicity

1st September 2021

The economic impact of the UK’s New Approach Methodologies sector

16th August 2021

Organ-on-chip applications in drug discovery: an end user perspective

13th August 2021

Predicting human drug permeability with a gut microphysiological system

11th August 2021

Microphysiological systems of the human liver, gut and linked liver-gut, to assess human drug absorption, metabolism and bioavailbility

9th August 2021

Liver-on-Chip and In Silico Modeling for Quantitative Drug Metabolism Studies

30th July 2021

Liver-on-a-chip

28th July 2021

PhysioMimix® support packages

28th July 2021

In vitro ADME services

28th July 2021

Pulmonary infection

28th July 2021

Hepatitis B

28th July 2021

Drug-induced liver injury (DILI)

28th July 2021

Metabolic dysfunction-associated steatohepatitis (MASH) in vitro

28th July 2021

Immune-mediated liver injury

28th July 2021

Drug bioavailability

28th July 2021

Drug metabolism in vitro

28th July 2021

Drug absorption

28th July 2021

ADME in vitro models

28th July 2021

PhysioMimix® Organ-on-a-chip models

28th July 2021

PhysioMimix® 3D validated cells

28th July 2021

PhysioMimix® dual-organ plate

28th July 2021

PhysioMimix® Barrier plate

28th July 2021

PhysioMimix® Liver plate

27th July 2021
Press releases

CN Bio licenses human gut organ microbiome modelling tool from MIT and Northeastern University

19th July 2021
Press releases

Lonza and CN Bio announce distribution agreement

15th July 2021
Blog

Of Mice and Men – Will human organ-on-a-chip disease models replace animal use?

29th June 2021
Press releases

CN Bio’s PhysioMimix® adopted by King’s College London to investigate chronic liver disease

24th June 2021
Business

Cell4Pharma enters supply agreement with CN Bio

9th June 2021

2D, or Not 2D

27th May 2021

IP-10 (CXCL10) Can Trigger Emergence of Dormant Breast Cancer Cells in a Metastatic Liver Microenvironment

24th May 2021

Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids

11th May 2021

The characterisation of a human two organ on a chip ( lung-Liver) system

9th May 2021

Pathologically Scarred by Fibrosis: How To Model and Quantify Human NASH in a Microphysiological System

5th May 2021
Press releases

CN Bio FDA collaboration expanded

21st April 2021

NAFLD vs MAFLD: could a name change impact the progression of liver disease research?

21st April 2021
Blog

NAFLD vs MASLD: could a name change impact the progression of liver disease research?

9th April 2021

Towards a Body-on-a-Chip: The Value of Multi-Organ MPS for Human-Relevant Drug Assessment

17th March 2021
Press releases

Introducing the PhysioMimix® OOC Multi-Organ Microphysiological System

9th March 2021

Engineering Mucosal Barriers

1st March 2021
Press releases

CN Bio awarded Innovate UK grant to develop single and multi-organ models for COVID-19 research

17th February 2021
Blog

Flowing to the beat of your heart

17th February 2021

Flowing to the Beat of Your Heart

11th February 2021

Multi-Organ in vitro organ-on-chip models for intestinal drug absorption and metabolism

11th February 2021

Gut-liver organ-on-a-chip combined with in silico modeling as a promising tool for investigation of mycophenolate mofetil pharmocokinetics

10th February 2021

Safety toxicology

9th February 2021

A Microphysiological Model of Metastatic Progression

1st February 2021

3D Cell Based Assays: Tips for Success

28th January 2021

Sitting down with… CN Bio

28th January 2021

Events

27th January 2021

How a novel in vitro Liver-on-a-Chip model of fatty liver disease is being used to help prevent a global healthcare crisis.

27th January 2021
Blog

How a novel in vitro Liver-on-a-chip model of fatty liver disease is being used to help prevent a global healthcare crisis.

15th January 2021

Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture

11th January 2021
Press releases

CN Bio’s PhysioMimix® technology receives FDA recognition

11th January 2021

Life in the Fastlane

11th January 2021
Blog

Life in the fastlane

9th January 2021

Testing on Humans

31st December 2020

Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism and accumulation

15th December 2020
Press releases

CN Bio and the University of Melbourne collaborate to advance therapies for respiratory complications in recovered COVID-19 patients

9th December 2020

The Rhythm of Life

9th November 2020

A Regulators Viewpoint

27th October 2020
Press releases

CN Bio to provide drug metabolism and safety toxicity testing services

21st October 2020

Predicting the future: humanised drug evaluation testing using organ-on-a-chip technology

16th October 2020

PhysioMimix® consumables

16th October 2020

Drug-induced liver injury (DILI) in vitro services

16th October 2020

In vitro Metabolic dysfunction-associated-steatohepatitis (MASH) Services

9th October 2020

Go with the Flow

9th September 2020

The Scars of Fat

8th September 2020
Press releases

CN Bio and Imperial College London Collaboration

3rd September 2020

Cell-Based Assays in 2D and 3D

15th August 2020

PhysioMimix Single-organ System Animation

9th August 2020

An Introduction to Organ‑On‑a‑Chip

5th August 2020
Press releases

CN Bio makes key senior appointments to support international commercial development

13th July 2020

PhysioMimix® OOC Microphysiological Systems

13th July 2020

In vitro contract research services

9th June 2020
Press releases

CN Bio and Cambridge University identify novel regulatory pathway driving NASH

8th June 2020

Bone morphogenetic protein 8B promotes the progression of Non-Alcoholic Steatohepatitis

1st June 2020

Microphysiological Systems Emerging as Powerful Tools for Drug Discovery

30th April 2020

Disease modeling

30th April 2020

Contact

30th April 2020

News

30th April 2020

Organ-on-a-Chip Resources

30th April 2020

Organ-on-a-chip applications

8th April 2020

About us

2nd March 2020
Press releases

CN Bio Innovations raises $9 million USD (c. £6.9 million GBP)

27th January 2020

Privacy statement

12th December 2019

Home

13th November 2019

A Microphysiological System for Studying Non-alcoholic Steatohepatitis

11th November 2019
Press releases

NASH drug discovery service launched at AASLD

11th August 2019

Comparing an in vitro Organ-on-Chip model of Non-Alcoholic Steatohepatitis to murine models and liver tissue from patients

1st May 2019
Press releases

Sydney’s AXT offers Organ-on-Chip systems in Asia Pacific region

28th February 2019
Press releases

CN Bio to bring 10 organs together on a chip

19th February 2019

“Liver-on-a-Chip” Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

22nd November 2018
Press releases

PhysioMimix® Human 3D Cell Culture wins Lab Innovation 2018 Award

11th August 2018

The PNPLA3 I148 variant enhances the disease phenotype of hepatic stellate cells in an in vitro model of non-alcoholic fatty liver disease

19th July 2018
Press releases

CN Bio Innovations’ Board names David Hughes as next Chief Executive Officer

23rd May 2018
Press releases

CN Bio launches PhysioMimix benchtop Human-Body-on-a-Chip device

1st May 2018
Media Coverage

Radio 4’s PM features CN Bio Human Organ-on-Chips

14th March 2018
Press releases

CN Bio and MIT announce 10 Organ-On-chip platform: Nature Scientific Reports

14th March 2018

Interconnected microphysiological systems for quantitative biology and phamarcology studies

2nd March 2018
Business

CN Bio MicroMix to be featured at AACR

23rd February 2018

Perfused human hepatocyte microtissues identify reactive metabolite-forming and mitochondria-perturbing hepatotoxins

22nd February 2018
Business

PharmaVentures interview: Will Organ-on-Chip technology provide the data regulators need in the future?

15th February 2018
Media Coverage

Hepatitis B research using CN Bio Organ-on-chips published in Nature Communications

14th February 2018

3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection

15th December 2017
Business

R&D 100 Award won by Vanderbilt team for tech being developed with CN Bio

1st November 2017
Press releases

CN Bio Innovations announces research collaboration with AstraZeneca to validate a new in vitro tool to predict optimised drug dosing regimens for multi-drug therapies

26th October 2017
Press releases

FDA signs collaborative agreement with CN Bio Innovations to use Organs-on-Chips to improve drug development and evaluation

11th October 2017
Press releases

Innovate UK awards grant to CN Bio Innovations and AstraZeneca to use Organs-on-Chips to evaluate the use of existing drugs to treat fatty liver disease

9th October 2017
Press releases

CN Bio Innovations announces licence of platform microfluidics technologies from Vanderbilt University

27th July 2017

Integrated gut and liver microphysiological systems for quantitative in vitro pharmacokinetics studies

1st July 2017

Integrated assessment of diclofenac biotransformation, pharmacokinetics and omics-based toxicity in a 3D human liver-immunocompetent co-culture system

1st July 2017

Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk

11th June 2017

Fully human in vitro gut-liver model of non-alcoholic steatohepatitis

11th May 2017

Microphysiological systems for studying interactions between the liver, gut and immune system

5th April 2017
Press releases

CN Bio Innovations announces license of worldwide rights to Hepatitis B programme from Bristol-Myers Squibb

1st March 2017

Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated MPS

3rd February 2017
Media Coverage

Huffington Post features CN Bio

1st January 2017

Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System

19th December 2016

Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform

30th November 2016
Media Coverage

CN Bio featured on the Discovery Channel

15th November 2016
Press releases

Dr Emma Sceats of organ-on-a-chip firm CN Bio Innovations wins Innovate UK’s infocus Women in Innovation award

11th August 2016

Three-dimensional human cell culture model for studying Non-Alcoholic Fatty Liver Disease

13th June 2016
Business

MIT and CN Bio to showcase world’s first 7 organ “Human-on-a-Chip” at Organ-On-Chip congress

6th June 2016
Business

CN Bio Sponsors the Organ-On-Chip world congress in Boston

11th May 2016

Identification And Evaluation Of Patient Serum Isolates As A Source Of Inoculum For 3D in Vitro Cell Culture: A Tool For Drug Discovery

4th January 2016
Business

CN Bio appoints Emma Sceats as CEO

2nd November 2015
Business

Imperial College London to present HBV data on CN Bio immune-competent liver model at AASLD The Liver Meeting

5th October 2015

Quantitative systems pharmacology approaches applied to MPS: Data interpretation and Multi-MPS integration

14th August 2015
Business

CN Bio appoints Dr David Hughes to board of directors

11th August 2015
Business

CN Bio Innovations features in Al Jazeera documentary “The Cure”

1st July 2015

Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused 3D human liver bioreactor

12th June 2015
Business

CN Bio Innovations announces deal with sixth pharmaceutical collaborator in 2015 and features in The Economist

2nd June 2015
Press releases

CN Bio Innovations announces research collaboration with Alnylam

27th May 2015
Business

CN Bio Innovations announces LiverChip research study with leading pharmaceutical company

11th May 2015

Three-dimensional perfused cell culture enhances the infectability of primary human hepatocytes with Hepatitis B virus

29th April 2015
Media Coverage

Bloomberg and Businessweek feature CN Bio Innovations’ LiverChip Platform

21st April 2015
Business

CN Bio Innovations announces Hepatitis B research collaboration with leading pharmaceutical company

19th March 2015
Business

CN Bio announces research collaboration with antisense discovery pioneers Isis Pharmaceuticals

2nd March 2015
Press releases

CN Bio announces research collaboration with gene silencing specialist Benitec Biopharma

23rd January 2015

Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device

12th January 2015
Press releases

CN Bio announces opening of new Biosafety Level 3 facility

8th January 2015

Addressing the Challenges of Low Clearance in Drug Research

17th November 2014
Business

CN Bio hosts popular Investigator Meeting and presents new HBV data at AASLD 2014

28th October 2014
Business

NIH Director highlights LiverChip in Compton Lecture

17th September 2014
Business

TSB Funds New Research by CN Bio into Fatty Liver Disease

2nd September 2014
Press releases

Imperial College London to present first public HBV data from CN Bio in vitro liver model

28th July 2014
Press releases

CN Bio Innovations marks World Hepatitis Day by signing research agreement with Imperial College London

4th April 2014
Business

CN Bio hires Director of Licensing

26th March 2014
Business

Liver disease to become a bigger killer than heart disease or cancer

10th February 2014
Press releases

Zyoxel Ltd to become CN Bio Innovations Ltd

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