Organ-on-a-Chip Resources

A guide to pre-validating cells for use in Organ-on-a-chip assays

If you are considering incorporating Organ-on-a-chip (OOC) technology into your workflow, you or your team may not know quite where to start?

Recreating Life in the Lab: How Predictive Human Organ Models are Transforming the Efficiency of Drug Discovery

Published on the International Biopharmaceutical Journal Volume 6 Issue 2

Learn about the New Approach Methodologies (NAMs) revolution and discover how Organ-on-a-chip technologies bridge the relevance gap between traditional preclinical assays and the human for better informed decision making across drug discovery.

Tech Blast | Organ-on-a-chip technologies

Created with BioTechniques

Senior Scientist, Dr Emily Richardson and Principal BioEngineer, Dr Dharaminder Singh discuss organ-on-a-chip. Including, how it differs to alternatives, what data can be generated and how to adopt the technology.

Summary report: Insights into new preclinical non animal models

A summary industry report compiled by Citeline looking into new preclinical non-animal models.

Full report: Insights into new preclinical non animal models

A complete industry report compiled by Citeline looking into new preclinical non-animal models.

What is organ-on-a-chip technology?

Created with BioTechniques

This video introduces what Organ-on-a-Chip technology is, how it works, its advantages, and why it is an important preclinical tool.

Top tips for integrating organ-on-a-chip technology into your workflow

Created with BioTechniques

Organ-on-a-chip (OOC) is a key emergent technology to add to your preclinical toolbox, offering an effective way to predict human responses to drugs in vitro. This Infographic shares six tips for getting started.

Alveolar and Bronchial Microphysiological Systems for respiratory infection research and therapeutics evaluation

Richardson et al

Learn about respiratory diseases and their impact on global health, as well as the potential of CN Bio’s technology in developing new pulmonary therapeutics.

Organ-on-a-chip Contract Research Services Brochure

Discover our full range of Organ-on-a-chip contract research services including ADME, NASH, DILI and Oncology as well as all the relevant endpoints.

A primary jejunum and primary hepatocyte multi-organ MPS

Find out how our gut-liver MPS recapitulates the physiological condition enabling oral drug dosing in vitro. This gut-liver model offers a vast improvement in the methods used to study PK or prodrugs.

Advanced pathophysiology mimicking lung models for accelerated drug discovery

Phan et al., 2023

This new publication highlights the importance of detailed critical evaluation of the human-relevance and reliability of in vitro models. We are thrilled to see the successes the Chrzanowski lab have had by using the PhysioMimix system to generate these novel MPS models which mimic healthy and normal human lungs.

Characterization of the effect of primary human hepatocytes (PHH) lots of functions in CN Bio Innovations Liver-Chip using acetaminophen

In this study, the FDA explore donor-to-donor variability in toxicology endpoints. Plus, how selecting the best combination of cells to accurately represent a given population is key to reducing the variability.