Blogs

A guide to pre-validating cells for use in Organ-on-a-chip assays
If you are considering incorporating Organ-on-a-chip (OOC) technology into your workflow, you or your team may not know quite where to start?
Articles

Recreating Life in the Lab: How Predictive Human Organ Models are Transforming the Efficiency of Drug Discovery
Published on the International Biopharmaceutical Journal Volume 6 Issue 2
Learn about the New Approach Methodologies (NAMs) revolution and discover how Organ-on-a-chip technologies bridge the relevance gap between traditional preclinical assays and the human for better informed decision making across drug discovery.
Podcasts

Tech Blast | Organ-on-a-chip technologies
Created with BioTechniques
Senior Scientist, Dr Emily Richardson and Principal BioEngineer, Dr Dharaminder Singh discuss organ-on-a-chip. Including, how it differs to alternatives, what data can be generated and how to adopt the technology.
Reports

Summary report: Insights into new preclinical non animal models
A summary industry report compiled by Citeline looking into new preclinical non-animal models.
Reports

Full report: Insights into new preclinical non animal models
A complete industry report compiled by Citeline looking into new preclinical non-animal models.
Videos and animations

What is organ-on-a-chip technology?
Created with BioTechniques
This video introduces what Organ-on-a-Chip technology is, how it works, its advantages, and why it is an important preclinical tool.
Infographic

Top tips for integrating organ-on-a-chip technology into your workflow
Created with BioTechniques
Organ-on-a-chip (OOC) is a key emergent technology to add to your preclinical toolbox, offering an effective way to predict human responses to drugs in vitro. This Infographic shares six tips for getting started.
Application notes

Alveolar and Bronchial Microphysiological Systems for respiratory infection research and therapeutics evaluation
Richardson et al
Learn about respiratory diseases and their impact on global health, as well as the potential of CN Bio’s technology in developing new pulmonary therapeutics.
Brochures & Flyers

Organ-on-a-chip Contract Research Services Brochure
Discover our full range of Organ-on-a-chip contract research services including ADME, NASH, DILI and Oncology as well as all the relevant endpoints.
Posters

A primary jejunum and primary hepatocyte multi-organ MPS
Find out how our gut-liver MPS recapitulates the physiological condition enabling oral drug dosing in vitro. This gut-liver model offers a vast improvement in the methods used to study PK or prodrugs.
Scientific publications

Advanced pathophysiology mimicking lung models for accelerated drug discovery
Phan et al., 2023
This new publication highlights the importance of detailed critical evaluation of the human-relevance and reliability of in vitro models. We are thrilled to see the successes the Chrzanowski lab have had by using the PhysioMimix system to generate these novel MPS models which mimic healthy and normal human lungs.
Posters

Characterization of the effect of primary human hepatocytes (PHH) lots of functions in CN Bio Innovations Liver-Chip using acetaminophen
In this study, the FDA explore donor-to-donor variability in toxicology endpoints. Plus, how selecting the best combination of cells to accurately represent a given population is key to reducing the variability.