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Organ-on-a-Chip Resources

Resource type

Area of interest

Blogs

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Immune-mediated DILI – Predicting the unpredictable!

Dr Anthony Berger discusses the limitations of the existing workflow and how organ-on-a-chip can help to predict the unpredictable, immune-mediated DILI.

Videos and animations

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Introducing PhysioMimix HT…

Our latest in the PhysioMimix organ-on-a-chip (OOC) range. The groundbreaking PhysioMimix HT (higher throughput)! Designed to overcome the adoption challenges of OOC technology.

Brochures & Flyers

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PhysioMimix Organ-on-a-Chip Brochure

Explore our full range of PhysioMimix organ-on-a-chip systems with our new brochure. Featuring our next-generation PhysioMimix HT (higher throughput).

Brochures & Flyers

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PhysioMimix Single-organ HT system

Discover the data behind our new groundbreaking PhysioMimix HT system and Liver48 plate. Plus why it is a game-changer in the industry.

Articles

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Organ-on-a-chip provides preclinical safety toxicologists with the tools to combat drug attrition

Learn how organ-on-a-chip technology is aiding toxicologists in de-risking drug-induced liver injury by providing human-specific safety data.

This article is taken from Select Science, February 2023

Articles

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Organ-on-a-chip models in drug development

Learn how organ-on-a-chip (OOC) technologies succeed where organoids and spheroids fail, bridging the remaining gap between existing 2D/3D models and the human.

This article is taken from Drug Discovery World, January 2023

Videos and animations

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About CN Bio…

Ever wondered what differentiates CN Bio, the people behind our brand, why we come to work every morning or our vision for the future? Here’s a snapshot of us in 3 minutes. We hope you enjoy it!

Blogs

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The U.S. FDA Modernization Act 2.0. Now the animal testing mandate is removed, what can be embraced in its place?

What is the FDA Modernization Act 2.0, and what does it mean?

Scientific publications

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Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay

Gallagher et al., 2022

This study shows the importance of normalization for paired MS-based multi-omics-OOC studies to accurately investigate highly toxic hazards and their effects on the human liver. Using VX, a highly toxic chemical compound, the study identifies VX-specific toxic effects on 3D liver tissues as well as specific hepatic cellular biomarkers and pathways affected by the toxic agent.

Webinars

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The Human Touch

Webinar Series 5 Episode 4

In this webinar, we highlight how the liver-on-a-chip system can be used to assess the impact of HSD17B13 inhibitors on fibrosis, human metabolism and lipid droplets.

Articles

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ADME Studies: Determining Promising Drug Compounds

Dr Abbas discusses factors that can affect the outcome of an ADME study, signs that a drug compound shows promise, red flags, and key parameters to determine safety and efficacy.

This article is taken from PharmTech, November 2022.

Webinars

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The Dash for NASH

Webinar Series 5 Episode 3

Find out how to: rapidly adopt an organ-on-a-chip (OOC) approach to NASH research, generate clinically translatable data from an industry-proven in vitro NASH model, and how OOC can help you unlock NASH disease mechanisms, and confirm drug efficacy and safety.

Speak to our experts

Speak directly with one of our OOC experts to see how our products and services can support your studies

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Latest news

  • Immune-mediated DILI – Predicting the unpredictable! March 16, 2023
  • CN Bio appoints Deepak Singh as Vice President of Sales and Marketing March 14, 2023
  • CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System   February 27, 2023

Upcoming events

MPS World Summit 2023 June 26-30, 2023

SLAS Europe 2023 May 22-26, 2023

SOT 2023 March 19-23, 2023

WORD 2023 March 22, 2022