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Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix OOC

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Learn more

Consumables

Multi-chip plates
3D validated cells
NASH-in-a-box
Bioavailability assay kit: Human 18
DILI assay kit: Human 24
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Organ-on-a-chip applications

Recreate healthy human physiology or complex human disorders in the lab


PhysioMimix organ-on-a-chip models are comprised of human cells and tissues whose phenotypes and functions reliably mimic those in vivo. By recreating human physiology in the lab, these models can be used for a myriad of applications that further our understanding of disease mechanisms, uncover potential therapeutic targets, and assist with the safe and efficacious development of potential therapeutics.

Explore application areas

arrow down | human organ-on-a-chip applications
LC12 plate in lab
Disease modeling cells

Disease modeling

Studying disease models provides insight into disease cause and progression. They help to identify potential therapeutic approaches and are used to assess drug efficacy. Our models functionally mimic the organ and give a realistic expression of the disease phenotype to ensure more clinically translatable data.

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Jump to area of interest

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
Safety toxicology cells

Safety toxicology

Predictive safety toxicology models that closely mimic in vivo function can more accurately predict drug safety and accelerate drug development by avoiding unexpected adverse effects in human trials.

Learn more

Jump to area of interest

Drug-induced liver injury
Immune-mediated liver injury
ADME cells

ADME

Determining the ADME properties of compounds is essential for lead optimization and candidate selection in early drug discovery. Single- and multi-organ models closely predict human in vivo pharmacokinetics for more informed decision-making.

Learn more

Jump to area of interest

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery

Speak to our experts

Request a meeting with one of our OOC experts to see how our products and services can support your studies

Request a meeting

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