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How in vitro human Gut/Liver models increase confidence in ADME estimations before human trials
Filed under: ADME, Drug absorption, Drug bioavailability, and Drug metabolism
This blog explores a world where novel multi-organ in vitro models, tiny replicas of the human intestine and liver, provide the key to unlocking a deeper understanding of how we Absorb, Distribute and Metabolize drugs.
Read more to discover why accurately estimating human ADME remains a challenge and a potential solution that enables greater confidence in lead candidates and a reduced risk of identifying poor oral bioavailability during first in human studies.