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PhysioMimix™ liver plate

Recreate 3D human liver tissues in vitro with the PhysioMimix Liver plate


PhysioMimix Liver plates enable primary human liver cells to be cocultured in 3D using an engineered scaffold that mimics the architecture of the liver capillary bed under perfusion.

3D scaffolds, embedded within 12 chips on the plate, are continually perfused by cell culture medium during experiments. ​

Perfusion provides continuous oxygen and nutrients for long-term Liver-on-a-chip culture, maintaining cell phenotypes and functions for at least four weeks.

Our plates are compatible with:

  • primary cells
  • induced-pluripotent stem cells
  • immortalized cell lines
  • circulating immune cells
  • precision-cut tissue slices
  • organoids

They are designed for use with PhysioMimix OOC systems and can be used for a variety of applications.


PhysioMimix Liver plate applications

Non-alcoholic steatohepatitis

Hepatitis B virus

Drug-induced liver injury

Immune-mediated toxicity

Drug metabolism


Related consumables

Dual-organ plate

3D validated cells

NASH-in-a-box kit


Learn more about PhysioMimix OOC
See other consumables
PhysioMimix™ Liver plate
PhysioMimix™ Liver plate well and cells close up

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Speak directly with one of our OOC experts to see how our products and services can support your studies

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Latest news

  • The FDA further expands collaboration with CN Bio to evaluate the PhysioMimix Multi-organ microphysiological system January 17, 2023
  • The U.S. FDA Modernization Act 2.0. Now the animal testing mandate is removed, learn what can be embraced in its place. January 9, 2023
  • CN Bio appoints Dr Paul Brooks as Chief Executive Officer December 19, 2022

Upcoming events

MPS World Summit 2023 June 26-30, 2023

SLAS Europe 2023 May 22-26, 2023

SLAS2023 February 25 - March 1, 2023