Recreate 3D human liver tissues in vitro with PhysioMimix Multi-chip Liver plates
PhysioMimix Liver-12 and -48 plates enable primary human liver cells to be co-cultured in 3D using an engineered scaffold that mimics the architecture of the liver capillary bed under perfusion.
3D scaffolds, embedded within the Multi-chip Liver-12 and -48 plates, are continually perfused by cell culture medium during experiments.
Perfusion provides continuous oxygen and nutrients for long-term Liver-on-a-chip culture, maintaining cell phenotypes and functions for at least four weeks.
Our plates are compatible with:
- primary cells
- induced-pluripotent stem cells
- immortalized cell lines
- circulating immune cells
- precision-cut tissue slices
- organoids
Which Liver plate matches your needs?
| Liver-12 plate | Liver-48 plate |
|---|---|
| Designed to create optimal conditions for primary human hepatocytes and non-parenchymal cells for deep mechanistic insights into drug, or disease mechanism | Designed to reduce cost/sample, increase throughput capabilities and provide data confidence for comparative drug response studies. |
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PhysioMimix OOC range compatibility
| Single-organ Systems | Multi-organ System | ||
| Standard | HT | Standard | |
| Liver-12 plate | |||
| Liver-48 plate | |||
PhysioMimix Liver plate applications
Related consumables
