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From Dose to Circulation: Determination of Drug Oral Bioavailability Using a Gut-Liver Microphysiological System
Determination of Drug Oral Bioavailability Using a Gut-Liver Microphysiological System
Filed under: ADME, Drug absorption, Drug bioavailability, and Drug metabolism
Webinar Series 4 Episode 4
In this webinar, Dr. Yassen Abbas will discuss how CN Bio’s gut-liver MPS can be used for in vitro determination of oral bioavailability. This application has been validated with drugs with known human bioavailability and with a mathematical model developed to enable prediction of oral bioavailability in silico.