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Pathologically Scarred by Fibrosis: How To Model and Quantify Human NASH in a Microphysiological System
How To Model and Quantify Human NASH in a Microphysiological System
Filed under: Disease modeling and NAFLD/NASH
Webinar Series 3 Episode 2:
Non-alcoholic steatohepatitis (NASH) is a widespread disease affecting up to ~12% of the US population – characterized by lipid accumulation in hepatocytes, infiltration of immune cells and fibrosis of the liver. Replicating liver fibrosis is a key element in any in vitro NASH model, however, it is normally poorly assessed, unquantifiable and has a limited dynamic range.