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How to Set Up an Organ-on-a-Chip System
Not Your Average Joe – Episode 3
Filed under: General OOC
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From Box to Bench in Just a Few Steps
Many researchers assume that adopting Organ-on-a-Chip technology requires complex installation procedures, specialist facilities or extensive technical support.
In reality, getting started can be much simpler than expected.
In this episode, Joe continues his Organ-on-a-Chip journey by setting up the PhysioMimix® Core for the first time. Follow along as our team demonstrates the installation process and shows how quickly researchers can move from delivery to experimentation.
“The goal isn’t to change your laboratory. It’s to help researchers access human-relevant biology using workflows that fit naturally into modern drug discovery.”
From Delivery to Discovery
Once your PhysioMimix® Core arrives, the next step is getting the system ready for use.
Designed as a compact benchtop platform, PhysioMimix® Core integrates into existing laboratory environments without the need for major infrastructure changes.
In this short demonstration, you’ll see how straightforward installation can be, helping new users build confidence before their first experiment.
What Does It Take to Get Started?
This episode walks through the key steps involved in preparing your PhysioMimix® Core for operation.
- How the PhysioMimix® Core is assembled
See how the main system components fit together. - What connections are required
Learn what is needed to get the system operational. - How quickly the platform can be prepared
Understand how researchers can move from installation to their first study. - What to expect before your first experiment
Gain confidence in the setup process before beginning tissue culture workflows.
Removing Barriers to Organ-on-a-Chip Adoption
One of the most common misconceptions about Organ-on-a-Chip technology is that implementation is complicated.
PhysioMimix® Core was designed to fit naturally into existing laboratory workflows, helping researchers adopt human-relevant models without extensive reconfiguration of their facilities.
For many teams, the biggest surprise is not the complexity of installation, but how quickly they can begin working with the system.
Built for Scientists
Designed to Fit Existing Workflows
esearchers need technologies that support science, not systems that create additional operational burden.
PhysioMimix® Core was developed to help researchers:
- Get started quickly
- Integrate with existing laboratory environments
- Follow established workflows
- Focus on generating data rather than managing equipment
The result is a platform designed to support adoption, adaptation and future scale as research needs evolve.
This content is part of a wider series:
Follow Joe’s journey as he discovers why Organ-on-a-Chip technology is easier to adopt than many researchers expect.
Watch other episodes

Series 1, Episode 1
Getting ready for Organ-on-a-chip – It’s easier than you think!

Series 1, Episode 2
Your First Day with the PhysioMimix® Core. What’s Included? Let’s unbox!

Series 1, Episode 3
How to Set Up an Organ-on-a-Chip System

Series 1, Episode 4
How to Seed Cells for Organ-on-a-Chip Experiments

Series 1, Episode 5
How to Dose Your Organ on a Chip Tissue

Series 1, Episode 6
How to Perform Endpoint Media Recovery for Analysis from Organ-on-a-Chip

Series 1, Episode 7
How to Collect Tissue Samples from Organ-on-a-Chip Experiments

Series 1, Episode 8
How to Scale Organ-on-a-Chip
Ready to Explore PhysioMimix® Core?
Discover why researchers are adopting Organ-on-a-Chip technology for safety assessment, ADME studies, disease modelling and human-relevant drug discovery.

