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Investigate the validated core application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix Core

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Consumables

Multi-chip plates
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- Liver-on-a-chip model
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August 10, 2026

Resource > Videos and animations >

How to Set Up an Organ-on-a-Chip System


Not Your Average Joe – Episode 3

Filed under: General OOC

cnb1731 nyaj 3 v1 | Organ-on-a-Chip setup

Video content if present

From Box to Bench in Just a Few Steps

Many researchers assume that adopting Organ-on-a-Chip technology requires complex installation procedures, specialist facilities or extensive technical support.

In reality, getting started can be much simpler than expected.

In this episode, Joe continues his Organ-on-a-Chip journey by setting up the PhysioMimix® Core for the first time. Follow along as our team demonstrates the installation process and shows how quickly researchers can move from delivery to experimentation.

“The goal isn’t to change your laboratory. It’s to help researchers access human-relevant biology using workflows that fit naturally into modern drug discovery.”

From Delivery to Discovery

Once your PhysioMimix® Core arrives, the next step is getting the system ready for use.

Designed as a compact benchtop platform, PhysioMimix® Core integrates into existing laboratory environments without the need for major infrastructure changes.

In this short demonstration, you’ll see how straightforward installation can be, helping new users build confidence before their first experiment.

What Does It Take to Get Started?

This episode walks through the key steps involved in preparing your PhysioMimix® Core for operation.

  • How the PhysioMimix® Core is assembled
    See how the main system components fit together.
  • What connections are required
    Learn what is needed to get the system operational.
  • How quickly the platform can be prepared
    Understand how researchers can move from installation to their first study.
  • What to expect before your first experiment
    Gain confidence in the setup process before beginning tissue culture workflows.

Removing Barriers to Organ-on-a-Chip Adoption

One of the most common misconceptions about Organ-on-a-Chip technology is that implementation is complicated.

PhysioMimix® Core was designed to fit naturally into existing laboratory workflows, helping researchers adopt human-relevant models without extensive reconfiguration of their facilities.

For many teams, the biggest surprise is not the complexity of installation, but how quickly they can begin working with the system.

Built for Scientists

Designed to Fit Existing Workflows

esearchers need technologies that support science, not systems that create additional operational burden.

PhysioMimix® Core was developed to help researchers:

  • Get started quickly
  • Integrate with existing laboratory environments
  • Follow established workflows
  • Focus on generating data rather than managing equipment

The result is a platform designed to support adoption, adaptation and future scale as research needs evolve.


This content is part of a wider series:

Follow Joe’s journey as he discovers why Organ-on-a-Chip technology is easier to adopt than many researchers expect.

Watch other episodes

cnb1641 nyaj e1 tmb v2 | Organ-on-a-Chip setup

Series 1, Episode 1

Getting ready for Organ-on-a-chip – It’s easier than you think!

cnb1642 nyaj e2 tmb v1 | Organ-on-a-Chip setup

Series 1, Episode 2

Your First Day with the PhysioMimix® Core. What’s Included? Let’s unbox!

cnb1731 nyaj 3 v1 | Organ-on-a-Chip setup

Series 1, Episode 3

How to Set Up an Organ-on-a-Chip System

cnb1732 nyaj 4 v1 | Organ-on-a-Chip setup

Series 1, Episode 4

How to Seed Cells for Organ-on-a-Chip Experiments

How to dose your Organ-on-a-Chip tissue Part 3

Series 1, Episode 5

How to Dose Your Organ on a Chip Tissue

cnb1716 nyaj 6 v2 1 | Organ-on-a-Chip setup

Series 1, Episode 6

How to Perform Endpoint Media Recovery for Analysis from Organ-on-a-Chip

cnb1730 nyaj 7 v1 | Organ-on-a-Chip setup

Series 1, Episode 7

How to Collect Tissue Samples from Organ-on-a-Chip Experiments

cnb1733 nyaj 8 v1 | Organ-on-a-Chip setup

Series 1, Episode 8

How to Scale Organ-on-a-Chip


Ready to Explore PhysioMimix® Core?

Discover why researchers are adopting Organ-on-a-Chip technology for safety assessment, ADME studies, disease modelling and human-relevant drug discovery.

Discuss Your Application
Explore PhysioMimix® Core
How to dose your Organ-on-a-Chip tissue Part 3

Video content if present

Tag iconGeneral OOC,  NYAJ

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Request a meeting with one of our OOC experts to see how our products and services can support your studies

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  • CN Bio announces expert speaker line-up and scientific program for inaugural Organ-on-a-chip e-Symposium October 1, 2026
  • CN Bio awarded Innovate UK grant to reduce animal use in pharmacokinetic studies August 12, 2026
  • Organ-on-a-chip trends shaping the next phase of human-relevant R&D from the MPS World Summit 2026 July 6, 2026
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