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Towards a Body-on-a-Chip: The Value of Multi-Organ MPS for Human-Relevant Drug Assessment

April 9, 2021 by

Resource > Webinars >

Towards a Body-on-a-Chip: The Value of Multi-Organ MPS for Human-Relevant Drug Assessment


The Value of Multi-Organ MPS for Human-Relevant Drug Assessment

Filed under: ADME, Disease modeling, Drug bioavailability, General OOC, and Safety toxicology

web s3e1 |

Video content if present

Towards a Body‑on‑a‑Chip

Watch our webinar to learn how single and multi-organ MPS can be incorporated into your drug discovery and development workflows and increase translation of preclinical assays.


Watch this webinar to learn:

  • What’s an MPS & how does it compare to standard approaches?
  • Latest multi-organ MPS developments and their value
  • How to design single- and multi-organ MPS experiments
  • The importance of generating liver-specific clinical endpoints in vitro

Microphysiological Systems (MPS), also known as organ-on-a-chip, generate human-relevant 3D cell culture models whose phenotypes and functions mimic individual in vivo organs. When therapeutics are added, these models can generate results that translate into clinical outcomes more reliably than standard in vitro techniques.

In the human body, however, no one tissue or organ operates in isolation. Could we achieve greater translation by interconnecting organ models? By linking gut and liver for example, can researchers better understand drug absorption and metabolism? Do reactive metabolites cause toxicity in different organs and at what doses? Do circulating immune cells promote inflammation and mediate toxicity?


Speaker Information:

Dr Tomasz Kostrzewski Dr Tomasz Kostrzewski

VP -Science & Technology
CN Bio Innovations

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Latest news

  • Immune-mediated DILI – Predicting the unpredictable! March 16, 2023
  • CN Bio appoints Deepak Singh as Vice President of Sales and Marketing March 14, 2023
  • CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System   February 27, 2023

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