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Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix OOC

physiomimix-single-and-multi-organ-on-a-chip-systems
Learn more

Consumables

Multi-chip plates
3D validated cells
NASH-in-a-box
Bioavailability assay kit: Human 18
DILI assay kit: Human 24
Learn more

Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the application areas that our PhysioMimix® products and services support

Learn more

Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
Learn more

Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
Learn more

ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
Learn more

Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

Learn more
icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

SOT 2025

July 10, 2024

Event > Conference >

SOT 2025


Visit our PhysioMimix® Organ-on-a-chip lab.

What are you waiting for?

cnb1337 sot 2025 event logo v1 | SOT
March 16-20, 2025
Orlando, Florida
Book a meeting at SOT 2025

What’s New?


Visit our PhysioMimix® Organ-on-a-chip lab – Stand #1429​

We have something very special to share with you this year. Head to our stand for an exclusive, hands-on Organ-on-a-chip experience like no other. We’re beyond excited to share this with you – and trust us, you won’t want to miss it!​

That’s not all, three lucky winners will also walk away with these adorable LEGO lab fume hoods. Whether you currently work in a lab, have in the past, or simply appreciate the combination of science and LEGO, this unique prize could be yours.​

Join us at Stand #1429 to learn more about our latest innovations, discover the surprise we have in store, and find out how you can enter to win.

cnb1346 cnbio lego v1 | SOT

dili kit | SOT

Meet the newest product in our PhysioMimix range

With the all-in-one PhysioMimix DILI assay kit, Human 24, you can now easily recreate our FDA-recognised assay in your own lab for robust, reliable, human–relevant results. ​

  • Unlock deep mechanistic insights beyond intrinsic DILI predictions ​
  • Identify unique complex, latent, and immune-related events​
  • Proven solution refined through years of industry collaboration​
  • Minimize reliance on animals and decrease hepatotoxicity risk

Presentations

Our Exhibitor Hosted Session​

Date: Mon 17 March​

Time: 12:15 – 13:15​

Room: W208B​

Free lunch included!!​

More info

Add to calendar

Toxicology Today: Liver microphysiological system use within routine safety testing and investigative tox​

Industry experts will discuss their current use of liver microphysiological systems (MPS) in advanced safety testing. Liver MPS complement and enhance existing approaches, enabling earlier identification of toxicity risks and the optimization of in vivo study design. The use of liver MPS to determine mechanisms of toxicity within investigative toxicology programs will also be reviewed, with a focus on evaluating ‘species-specific’ toxic events using cross-species MPS assays.​

Presenter: Dr. Emily Richardson and Dr. Tomasz Kostrzewski, CN Bio​

Add to calendar

Head over to this podium session​

Date: Tues 18 March​

Time: 11:00 – 12:30​

Room: W304E

More info

Add to calendar

​

Assessing the Metabolic Competence of In Vitro Models and Their Applicability in Regulatory Toxicology​

Presentations from:​

  • Emily Richardson, CN Bio
  • Hans Raabe, Institute for In Vitro Sciences Inc​
  • Warren Casey, NIEHS/DTT​
  • Nuria Roldan, PETA Science Consortium International e.V.​
  • Patrick J. Hayden, BioSurfaces Inc
  • ​

Add to calendar

Visit our poster​ presentation

Date: Weds 19 March​

Time: 09:15 – 11:45​

Room: ToxExpo Hall

More info

Add to calendar

​

4713: A human liver microphysiological system for assessing mechanisms of toxicity during drug development​

​Poster board: K554​

​Presenter: Dr. Ovidiu Novac, CN Bio

Add to calendar​


Meet the team at SOT

Tom | SOT

Tom

Dr Kostrzewski has more than 15 years of experience in molecular and cellular biology research. He joined CN Bio in 2015 and was promoted to Director of Biology in 2018 with responsibility for biological model development and collaborative research projects with academia, pharma, and regulators. In 2021 he was promoted to VP of Science and Technology and then to Chief Scientific Officer in 2023, with responsibility for all technical activities, including developing new products, technologies, and assays, as well as contract research services. Dr Kostrzewski has managed multiple grant-funded collaborative projects at CN Bio and is currently the project lead for the collaborative project between CN Bio and the FDA. He has published more than twelve peer-reviewed scientific articles in the last five years and submitted several patent applications.

Prior to joining CN Bio, he worked at Imperial College London in the Department of Life Sciences studying immune cell development and stem cell differentiation, as well as at GlaxoSmithKline working in biopharmaceutical drug discovery and development. Dr Kostrzewski holds three degrees from the University of Sheffield and Imperial College London in Cell and Molecular Biology.

adiran

Adrian

A seasoned business developer with extensive commercial experience in the life science sector, Adrian Rea joined CN Bio as the European Director of Sales in June 2022. He brings valuable experience in the 3D cell culture market from his most recent role at InSphero, where he was responsible for developing business opportunities in European and Asian markets. He was previously Sales Director at Enzo Life Sciences, where he managed the restructuring of the global distributor sales channels and expanding the European sales operations. Adrian graduated from the University of Glasgow and received his PhD in pharmacology from Glasgow Caledonian University. 

Joe | SOT

Joe

Joe Parisi is a Commercial Leader with 14 years’ experience in the life science sector. Joe joined CN Bio as the Americas Director of Sales in December 2023. He comes to CN Bio with valuable startup experience most recently at IsoPlexis and Purigen Biosystems, where he was responsible for building commercial opportunities across the US West. He was previously Sales Director at PhenomeX (now Bruker Cellular Analysis), where he managed the proteomics team in the US West focusing on capital equipment sales for single-cell functional analysis. Joe graduated from the University of Illinois Champaign-Urbana with a BSc in Molecular and Cellular Biology.

emily | SOT

Emily

Dr Emily Richardson is a Lead Scientist in the R&D team at CN Bio. She joined the team in 2020 as a Senior Scientist and lead the development of the PhysioMimix® lung and lung-liver MPS models. Emily is highly experienced in the application of complex cell biology to drug discovery, having previously worked in cellular therapeutics in an industry setting and as a trained biochemist with specialty in molecular biology. She completed her PhD at the University of Leicester, using 3D cell culture to determine molecular mechanisms driving highly metastatic lung cancers. She now leads R&D projects within the CN Bio team revolving around toxicology in the liver and the lung MPS, as well as driving collaborative projects with various academic, industry and regulatory partners.

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Anthony

Dr. Anthony Berger is CN Bio’s US-based Field Application Scientist, providing support for the PhysioMimix® Organ-on-Chip benchtop platform. Anthony has an extensive research background in 3D cell culture, biomaterials, and microfluidics, focusing on how the microenvironment influences cellular decision-making. He is a proponent of complex 3D in vitro models and desires to decrease the barrier to entry of these technologies. Anthony received his BS from Indiana University (US), PhD from the University of Wisconsin (US), and completed a postdoctoral fellowship at Temple University (US).

Sung BW | SOT

Sung

A seasoned life science professional with over 20 years of experience in product management, product marketing, and commercial leadership, Sung Lee joined CN Bio as a Director of Product Management in October 2024. He brings valuable experience in the assay kit market from his most recent role at Abcam, where he was the global lead as the Senior Product Director for the Assay Kits and Protein product portfolio. He has held various leadership roles at renowned companies like Abcam (Danaher Company), Epitomics (‘The Rabbit Monoclonal Company’), and Life Technologies (Thermo Fisher Scientific). Sung’s education background includes business certifications from Cambridge Judge Business School and Wharton Business School, and a degree in Molecular and Developmental Biology from the University of California, Santa Cruz.

Ovi grey for website CURRENT | SOT

Ovi

Dr Ovidiu Novac is a Senior Scientist at CN Bio and a knowledgeable organ-on-a-chip (OOC) expert. Ovi performed on several assay development projects as lead biological scientist, is a knowledgeable organ-on-a-chip (OOC) expert, and has experience in assessing drug induced liver injury in vitro. Ovi has a background in the developmental stage of pharmaceutical and dermatological formulations and their performance assessment on human skin tissue ex vivo (topical and transdermal), and for strategic planning for further evaluation. During time spent in the pharma industry he contributed to delivering high quality results used for marketing purposes and in regulatory submissions. Ovi holds a BSc in biomaterials and prosthetic technologies and a PhD in chemistry and has been involved in research on controlled drug delivery systems since 2006.

SOT 2025

Book a meeting at SOT 2025

Speak to our experts

Request a meeting with one of our OOC experts to see how our products and services can support your studies

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