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Discover the applications


Investigate the validated core application areas that our PhysioMimix® products and services support

Learn more

Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
Learn more

Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
Learn more

ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

Learn more
icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix Core

cnb1476_physiomimix-core_mark_mocks_system_v2
Learn more

Consumables

Multi-chip plates
3D validated cells
Learn more

Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

May 29, 2026

Event > Conference >

ISSX Europe 2026


The 16th European ISSX Meeting will explore how advances in DMPK are transforming benchside research into bedside reality, shaping the next chapter of drug discovery and development.

Visit our booth to learn more about the most advanced in vitro models available. Discover the PhysioMimix® Core & learn about CN Bio’s role in the recent FDA ISTAND-accepted cross platform evaluation of commercial liver MPS.

cnb1613 issx26 event logo v1 | ISSX Europe 2026
29 June - 02 July, 2026
Basel, Switzerland
Book a meeting at ISSX Europe 2026

Where to find us at the ISSX Europe 2026!


Visit us at ISSX Europe – Stand # 19

Join us at our booth to discover how you can capture critical biological mechanisms that conventional models often miss. With our multi-organ microphysiological systems (MPS), you can isolate tissue-specific ADME parameters to de-risk your pipeline with human-relevant translational data.

Our approach enables physiological profiling across critical pharmacokinetic areas. This includes evaluating human oral bioavailability through first-pass metabolic and individual gut and liver contributions, as well as generating precise metabolism, clearance, and metabolite production data. Furthermore, our platform allows you to quantify dynamic transport for absorption profiles and separate intricate drug-drug interaction (DDI) risks across organs.

So, let’s change the game, together with a platform like no other. Meet the new easy to adopt, adapt and scale MPS – PhysioMimix® Core. Interact with its Multi-chip consumables plates and explore our range of validated protocols.

Our dedicated team will be at hand to answer your questions and share over a decade of Organ‑on‑a‑Chip (OOC)/ MPS expertise. Discover how you can enhance data translatability, optimize in vivo study design, and support confident preclinical decision‑making using more predictive, human‑relevant approaches that are in line with regulatory roadmaps to reduce animal testing.

Book a meeting at ISSX Europe 2026
cn-bio_anoatomy_on-light

physiomimix core front 1 | ISSX Europe 2026

What’s New?

Explore the PhysioMimix® Core!

The only microphysiological system that’s easy to adopt, adapt and scale right away. Validated for single-organ, multi-organ, and higher throughput configurations, PhysioMimix Core offers a unified and flexible solution that:

  • Ensures a simple start for immediate productivity
  • Offers flexibility to grow with your needs​
  • Matches immediate and future demand
  • Is validated for disease modeling, safety toxicology and ADME CoU.

Can also be accessed via our Contract Research Services.

Find Out More

Attend our plenary presentation:

A primary human Gut/Liver microphysiological system to estimate human oral bioavailability.

TBC

Date: 01 July 2026, Wednesday

Time: 17:00 – 18:30

Session: Plenary Session 2

Room: TBC

Presenters: Dr. Yassen Abbas


Meet the CN Bio Team at ISSX Europe 2026

Tom3 | ISSX Europe 2026

Tomasz

CSO

Dr Kostrzewski has more than 15 years of experience in molecular and cellular biology research. He joined CN Bio in 2015 and was promoted to Director of Biology in 2018 with responsibility for biological model development and collaborative research projects with academia, pharma, and regulators. In 2021 he was promoted to VP of Science and Technology and then to Chief Scientific Officer in 2023, with responsibility for all technical activities, including developing new products, technologies, and assays, as well as contract research services. Dr Kostrzewski has managed multiple grant-funded collaborative projects at CN Bio and is currently the project lead for the collaborative project between CN Bio and the FDA. He has published more than twelve peer-reviewed scientific articles in the last five years and submitted several patent applications.
    adiran

    Adrian

    Director of Sales (Europe)

    A seasoned business developer with extensive commercial experience in the life science sector, Dr. Adrian Rea joined CN Bio as the European Director of Sales in June 2022. He brings valuable experience in the 3D cell culture market from his previous role, at InSphreo, where he was responsible for developing business opportunities in European and Asian markets. He was previously Sales Director at Enzo Life Sciences, where he managed the restructuring of the global distributor sales channels and expanding the European sales operations.

    Adrian graduated from the University of Glasgow and received his PhD in pharmacology from Glasgow Caledonian University.
      Yass 2 1 | ISSX Europe 2026

      Yassen

      Biology Group Leader

      Dr. Yassen Abbas is a Lead Scientist at CN Bio. He completed an MEng in chemical engineering at The University of Edinburgh and joined the European Space Agency as a graduate engineer. He later received a PhD from the University of Cambridge and completed a postdoc fellowship, also at Cambridge on the development of a tissue engineered model of the human endometrium. He has experience with real-time sensor technology, organoids and development of in vitro tissue models using human primary cells. Dr Abbas has published five peer-reviewed scientific articles, four as first author.
        Sarah P BW | ISSX Europe 2026

        Sarah

        Director of Marketing

        Dr. Sarah Payne brings a rare blend of deep scientific expertise and commercial acumen to her role as Marketing Director at CN Bio, which she joined in 2020.

        With a BSc in Biochemistry with Toxicology, a PhD in Receptor Pharmacology, and years of commercial experience in the life sciences sector, she has a unique ability to translate complex science into commercially successful market strategies.

          ISSX Europe 2026

          Book a meeting at ISSX Europe 2026

          Speak to our experts

          Request a meeting with one of our OOC experts to see how our products and services can support your studies

          Request a meeting

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          • Do MHRA and FDA guidelines on non-animal methods in drug development align? March 27, 2026
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