3D Cell Culture

3D cell culture is a key tool in the study of human cells and organs. The biomimetic structures formed better replicate the microenvironments, cell-cell interactions and biological processes that occur in vivo, bridging the gap between traditional cell culture and human studies.

Other benefits include enabling more co-culture options, creating polarised tissues and allowing for longer term growth. In drug development this allows scientists to design assays which mimic how organs absorb, distribute, metabolize, and eliminate (known as ADME) drugs and other chemicals in vitro.

3D Cell Culture Using PhysioMimix™

Our microphysiological systems (MPS) allow researchers to set up human 3D cell culture assays and generate results quickly.

Cells cultured on 3D scaffolds embedded in the wells on PhysioMimix™ plates:

  • Are continually perfused by cell culture medium during experiments
  • Create optimal culture conditions for functional human organ microtissues
  • Allow scientists to predict the effects of compounds on human organs

In 2018, the PhysioMimix™ 3D cell culture system won the Innovation Award at the UK’s largest laboratory event, Lab Innovations, selected from hundreds of innovative laboratory products

Setting Up 3D Cell Culture Experiments

PhysioMimix™ can be used to run 3D cell culture assays for a range of cell formats:

  • fresh or cryopreserved cells
  • pre-formed tissues or organoids
  • organ and tissue slices
  • customised or commercial inserts

Human organ
mimics

Powerful new
data

Translatable
results

COMPANY HEAD OFFICE INFORMATION:

CN Bio Innovations Limited
BioPark Hertfordshire
Broadwater Road
Welwyn Garden City
Hertfordshire
AL7 3AX, UK

+44 (0) 1707 358 739
enquiries@cn-bio.com

FOR PRODUCT, SERVICES AND MARKETING ENQUIRIES:

enquiries@cn-bio.com
+44 (0) 1707 358 739

CN BIO INNOVATIONS LIMITED REGISTERED OFFICE:

30 Upper High Street, Thame,
Oxfordshire, OX9 3EZ.

Registered No. 06517359.
VAT No. 978184563

PhysioMimix is

Get started with PhysioMimix™

1. GETTING STARTED

Install the PhysioMimix™ T1 System easily in your own lab – you can be ready to start with human-organ based studies in less than an hour.

2. SEED

To begin your Organs-on-Chip cultures, dock the MPS multiwell plate onto the device’s base unit. Prime with cell culture media, and seed with cells.

3. CULTURE

PhysioMimix™ is compatible with standard cell culture incubators. Flow rates can be programmed to enable long-term experiments.

4. MULTI-ORGAN ANALYSIS

Set up either single- or multi-organ experiments. Select different cell types and different combinations and run these experiments simultaneously.


5. DOSE

The PhysioMimix™ MPS plates’ open-well design allows easy access to cells and media for dosing, sampling and analysis.


6. ANALYZE

Use the data from your PhysioMimix™ experiments to help you understand and predict the response of human cells to drugs, additives, cosmetics.

Human organ
mimics

Powerful new
data

Translatable
results

COMPANY HEAD OFFICE INFORMATION:

CN Bio Innovations Limited
BioPark Hertfordshire
Broadwater Road
Welwyn Garden City
Hertfordshire
AL7 3AX, UK

+44 (0) 1707 358 739
enquiries@cn-bio.com

FOR PRODUCT, SERVICES AND MARKETING ENQUIRIES:

enquiries@cn-bio.com
+44 (0) 1707 358 739

CN BIO INNOVATIONS LIMITED REGISTERED OFFICE:

30 Upper High Street, Thame,
Oxfordshire, OX9 3EZ.

Registered No. 06517359.
VAT No. 978184563


We like to contact you about: exciting events, campaigns and information about the new products (please note we DO NOT pass on your details to any other organisations), you can opt out of receiving communications at any time.
By submitting your message, you acknowledge that you have read and understood the Privacy Policy

I confirm that I would like CN Bio to stay in touch

We like to contact you about: exciting events, campaigns and information about the new products (please note we DO NOT pass on your details to any other organisations), you can opt out of receiving communications at any time.
By submitting your message, you acknowledge that you have read and understood the Privacy Policy

I confirm that I would like CN Bio to stay in touch

We like to contact you about: exciting events, campaigns and information about the new products (please note we DO NOT pass on your details to any other organisations), you can opt out of receiving communications at any time.
By submitting your message, you acknowledge that you have read and understood the Privacy Policy

I confirm that I would like CN Bio to stay in touch