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Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix Core

cnb1476_physiomimix-core_mark_mocks_system_v2
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Consumables

Multi-chip plates
3D validated cells
NASH-in-a-box
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the validated core application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Organ-on-a-Chip Resources

Featured

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Videos and animations

PhysioMimix®Core microphysiological system video – a universal end-to-end Organ-on-a-chip solution

The PhysioMimix Core provides a universal end-to-end solution for recreating complex human physiology in vitro. The only microphysiological system (MPS) platform that delivers validated performance across single-organ, multi-organ, and higher-throughput configurations.

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Articles

The future of liver health: AI and human models

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Blogs

Integrating In Silico Tools with Organ-on-a-Chip to advance ADME studies

Knowing a drug’s bioavailability during lead optimization is crucial as it directly influences dosing strategy, therapeutic efficacy, safety margins, and formulation design.

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Application notes

Enhance IVIVE with cross-species Liver MPS DILI assays

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Application notes

Accelerating DILI Prediction: A High-Throughput Liver-on-a-Chip Solution

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Application notes

A liver microphysiological system to study the delivery and efficacy of oligonucleotide-based therapeutics

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Application notes

Evaluating a human DILI assay’s ability to unlock complex mechanisms of toxicity

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Application notes

Developing a translational biomarker panel for use in pre-clinical advanced in vitro studies of Non-alcoholic steatohepatitis

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Application notes

Connecting the gut and liver

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Application notes

Alveolar and Bronchial Microphysiological Systems for respiratory infection research and therapeutics evaluation

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Application notes

Human liver microphysiological system for predicting the drug-induced liver toxicity of differing drug modalities

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Application notes

Microphysiological system for studying fatty liver disease and its impact on drug-induced liver injury

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Application notes

Improved prediction of oral bioavailability using a gut-liver microphysiological system

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Application notes

Drug metabolism in a gut-liver microphysiological system

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Application notes

Predicting human drug permeability with a gut microphysiological system

Speak to our experts

Request a meeting with one of our OOC experts to see how our products and services can support your studies

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Latest news

  • Taking organoids to the next level January 14, 2026
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  • CN Bio launches all-in-one Organ-on-a-chip system, PhysioMimix® Core October 14, 2025
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