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6 Challenges in ADME Drug Development
Explore the current challenges in profiling preclinical human ADME through key publications.
Filed under: ADME and Drug bioavailability
Can advances in the human relevance of preclinical models improve estimations for safer and more efficient drug development?
- Change the risk calculus by broadening the ADME toolbox with human relevant assays
- Importance of a varied toolbox, combing in vitro, in vivo and in silico
- Why identifying human intestinal first-pass metabolism is crucial?
- Is the current ADME toolbox fit for advanced drug modalities?