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Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix OOC

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Consumables

Multi-chip plates
3D validated cells
NASH-in-a-box
Bioavailability assay kit: Human 18
DILI assay kit: Human 24
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-dili-tox-150x150.png Drug-induced liver injury
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Organ-on-a-Chip Resources

Featured

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Blogs

Integrating In Silico Tools with Organ-on-a-Chip to advance ADME studies

Knowing a drug’s bioavailability during lead optimization is crucial as it directly influences dosing strategy, therapeutic efficacy, safety margins, and formulation design.

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Brochures & Flyers

PhysioMimix Bioavailability assay kit: Human 18 brochure

Modernize your workflow with the only in vitro bioavailability assessment tool on the market. Elevate your workflow with our all-in-one Bioavailability assay kit containing everything you need to recreate our human in vitro Gut/Liver-on-a-chip model and Bioavailability assay in your laboratory.

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Videos and animations

PhysioMimix® bioavailability assay kit: Human 18 for simultaneous oral and intravenous in vitro bioavailability profiling

Discover the PhysioMimix® Bioavailability assay kit: Human 18, the only in vitro tool for profiling human bioavailability. This Organ-on-a-chip solution bridges the gap between in vitro and in vivo studies, enhancing preclinical ADME testing for CROs, pharma, and biotech. Explore how it streamlines lead optimization and improves drug development accuracy.

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Topic Area:
ADME(9)
Drug absorption(1)
Drug bioavailability(4)
Drug metabolism(2)
Oligonucleotide delivery(1)
Disease modeling(10)
COPD(0)
HBV(0)
MASLD/MASH(4)
Oncology(1)
Pulmonary infection(1)
General OOC(8)
Safety toxicology(11)
DILI(7)
Genotoxicity(1)
Immune-mediated liver injury(1)
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Webinars(30)
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Webinars

MPS and In Silico Modeling: The next generation of bioavailability prediction

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Webinars

Get Ready for Regulatory Changes and the Future of NAMs

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Webinars

Harnessing Liver-on-a-chip models for drug safety

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Webinars

Advancing oligonucleotide therapies with liver-on-a-chip models

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Webinars

A Gut/Liver microphysiological system for profiling human oral bioavailability

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Webinars

Go/No-Go

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Webinars

User Group Meeting 2024 – Recap

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Webinars

Lost in Translation

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Webinars

Organ-on-a-Chip: Big Questions Surrounding Regulation and the Roadmap to Broad Adoption

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Webinars

Beyond hepatotoxicity red flags

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Webinars

Set yourself up for success with organ-on-a-chip

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Webinars

Normalization of organ-on-a-chip samples

Speak to our experts

Request a meeting with one of our OOC experts to see how our products and services can support your studies

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Latest news

  • CN Bio adds computational modelling capabilities to ADME services for enhanced bioavailability profiling September 1, 2025
  • Integrating In Silico Tools with Organ-on-a-Chip to advance ADME studies July 15, 2025
  • NIH to prioritize human-based research technologies & reduce animal use in research July 7, 2025
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