Liver-On-Chip

 

The liver is a key organ in the study of drug metabolism and toxicology. Understanding the way in which a drug is processed by the liver and any adverse effects caused is crucial in drug development. Liver disease is also a major concern, with approximately 850 million people worldwide living with chronic liver diseases.

 

CN-Bio has developed a Liver-on-Chip MPS specifically designed for the research of drug metabolism, toxicology and liver diseases.

Liver Cell Model

CN Bio’s multi-well PhysioMimix™ Liver-on-Chip (LC12) plates are ideally suited for assays involving primary liver cell cultures or co-cultures. These provide researchers with detailed information for identifying liver toxicity markers, modelling liver disease and studying drug metabolism.

Our MPS devices use scaffolds containing microtissues that are continuously perfused providing nutrients, oxygen and mechanical stimuli. This enables extended (> 1 month) maintenance of phenotypically intact three-dimensional (3D) primary human hepatocyte cells, with highly reproducible results.

The PhysioMimix™ Liver-on-Chip plates are designed to provide optimal perfused 3D cell culture conditions for:

  • Primary liver parenchymal cells and non-parenchymal cells
  • Precision cut tissue slices
  • Organoids
  • Customised inserts

Human organ
mimics

Powerful new
data

Translatable
results

COMPANY HEAD OFFICE INFORMATION:

332 Cambridge Science Park
Milton Road
Cambridge
CB4 0WN

+44 (0) 1223 737941
enquiries@cn-bio.com

FOR PRODUCT, SERVICES AND MARKETING ENQUIRIES:

+44 (0) 1223 737941
enquiries@cn-bio.com

CN BIO INNOVATIONS LIMITED REGISTERED OFFICE:

30 Upper High Street, Thame,
Oxfordshire, OX9 3EZ.

Registered No. 06517359.
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