Liver-On-Chip
The liver is a key organ in the study of drug metabolism and toxicology. Understanding the way in which a drug is processed by the liver and any adverse effects caused is crucial in drug development. Liver disease is also a major concern, with approximately 850 million people worldwide living with chronic liver diseases.
CN-Bio has developed a Liver-on-Chip MPS specifically designed for the research of drug metabolism, toxicology and liver diseases.
Liver Cell Model
CN Bio’s multi-well PhysioMimix™ Liver-on-Chip (LC12) plates are ideally suited for assays involving primary liver cell cultures or co-cultures. These provide researchers with detailed information for identifying liver toxicity markers, modelling liver disease and studying drug metabolism.
Our MPS devices use scaffolds containing microtissues that are continuously perfused providing nutrients, oxygen and mechanical stimuli. This enables extended (> 1 month) maintenance of phenotypically intact three-dimensional (3D) primary human hepatocyte cells, with highly reproducible results.
The PhysioMimix™ Liver-on-Chip plates are designed to provide optimal perfused 3D cell culture conditions for:
- Primary liver parenchymal cells and non-parenchymal cells
- Precision cut tissue slices
- Organoids
- Customised inserts
Human organ
mimics
Powerful new
data
Translatable
results
COMPANY HEAD OFFICE INFORMATION:
CN Bio Innovations Limited
BioPark Hertfordshire
Broadwater Road
Welwyn Garden City
Hertfordshire
AL7 3AX, UK
+44 (0) 1707 358 739
enquiries@cn-bio.com
FOR PRODUCT, SERVICES AND MARKETING ENQUIRIES:
enquiries@cn-bio.com
+44 (0) 1707 358 739
CN BIO INNOVATIONS LIMITED REGISTERED OFFICE:
30 Upper High Street, Thame,
Oxfordshire, OX9 3EZ.
Registered No. 06517359.
VAT No. 978184563