Today, we signed a supply agreement with Dutch Company Cell4Pharma to access their industry-validated conditionally immortalized Renal Proximal Tubule Epithelial Cell (ciPTEC) lines for use with our PhysioMimix® Organ-on-a-chip (OOC) Systems.
Our PhysioMimix OOC systems, which are designed to generate translational single, and multi-organ in vitro models, will be used to culture ciPTECs under perfusion flow to recreate a human kidney model for research use, ADME profiling and nephrotoxicity testing.
Improved models of the human kidney are urgently required within preclinical drug development to more accurately identify and eliminate the 20% of compounds that currently fail in the clinic due to nephrotoxicity.
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