Recreate healthy human physiology or complex human disorders in the lab
PhysioMimix organ-on-a-chip models are comprised of human cells and tissues whose phenotypes and functions reliably mimic those in vivo. By recreating human physiology in the lab, these models can be used for a myriad of applications that further our understanding of disease mechanisms, uncover potential therapeutic targets, and assist with the safe and efficacious development of potential therapeutics.
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Disease modeling
Studying disease models provides insight into disease cause and progression. They help to identify potential therapeutic approaches and are used to assess drug efficacy. Our models functionally mimic the organ and give a realistic expression of the disease phenotype to ensure more clinically translatable data.
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Safety toxicology
Predictive safety toxicology models that closely mimic in vivo function can more accurately predict drug safety and accelerate drug development by avoiding unexpected adverse effects in human trials.
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ADME
Determining the ADME properties of compounds is essential for lead optimization and candidate selection in early drug discovery. Single- and multi-organ models closely predict human in vivo pharmacokinetics for more informed decision-making.