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PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix OOC

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Learn more

Consumables

Multi-chip plates
3D validated cells
NASH-in-a-box
Bioavailability assay kit: Human 18
DILI assay kit: Human 24
Learn more

Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

MPS World Summit 2025

December 17, 2024

Event > Conference >

MPS World Summit 2025


40+ international organizations and companies participate in annual MPS World Summits to present the latest scientific achievements, discuss the advances and challenges, and enable communication between newly interested scientists and pioneers of the MPS field.

In 2025, the MPS World Summit will be in Brussels, Belgium. Join us to find out what’s new from CN Bio, including a new contract research service which launches on June 10th at the event, plus four posters showcasing our latest MPS advancements.

cnb1292 mps 2025 event logo v1 | MPS World Summit
June 9-13, 2025
Brussels, Belgium
Book a meeting at MPS

Visit us at MPS!

Our dedicated team of creative problem solvers will be available to answer questions and share over a decade of MPS expertise with you!

We look forward to meeting you to discuss how our PhysioMimix® range of products and services can help to improve the predictivity of your workflows and address your current workflow limitations – such as modelling the immune system in vitro and testing the safety of new modality drugs following the recent FDA announcement.

Get familiar with our human-relevant single- and multi-organ in vitro models/ assays/ all-in-one kits and contract research services.

Learn more about their proven track record for delivering clinically translatable results from our experts.

And discover our NEW Contract Research Service, launching on the 10th June!

People at the CN Bio exhibition stand

An image of the PhysioMimix DILI assay kit: Human 24

Meet the newest product in our PhysioMimix range

With the all-in-one PhysioMimix DILI assay kit, Human 24, you can now easily recreate our FDA-recognised assay in your own lab for robust, reliable, human–relevant results. ​

  • Unlock deep mechanistic insights beyond intrinsic DILI predictions ​
  • Identify unique complex, latent, and immune-related events​
  • Proven solution refined through years of industry collaboration​
  • Minimize reliance on animals and decrease hepatotoxicity risk

Discover the latest MPS advancements at our poster presentations

Poster 66

Date: Thurs 12 June

Time: 10:00 – 11:30am

More info

Combining a primary gut/liver MPS with mathematical modelling for a mechanistic understanding of midazolam’s ADME profile and oral bioavailability

Here, we present a dual-organ MPS that simulates oral and IV drug delivery. Combined with mathematical modelling, we demonstrate the ability to mechanistically profile and extract multiple ADME parameters including oral bioavailability from one experiment.​

Presenter: Dr. Yassen Abbas, CN Bio

Poster 53

Date: Thurs 12 June

Time: 10:00 – 11:30am

More info

​

A liver microphysiological system to study the delivery and efficacy of oligonucleotide-based therapeutics ​

New therapeutic modalities, such as siRNA and ASOs, can treat diseases unreachable by traditional drugs. This study tested GalNAc-conjugated oligonucleotides on primary human hepatocytes in a PhysioMimix® Liver microphysiological system, showing greater gene knockdown compared to non-conjugated versions. These effects were dose-dependent, demonstrating the system’s effectiveness for long-term, human-relevant in vitro modeling.

Presenter: Dr. Oliver Culley, CN Bio

Poster 494

Date: Thurs 12 Jun

Time: 10:00 – 11:30am​

More info

​

Evolving translation: the use of human and preclinical animal liver microphysiological systems for improved understanding of species-specific drug-induced liver injury 

Together, these data demonstrate the in vivo translatability of MPS and its importance as a drug development tool. Animal MPS can be used in parallel with human MPS to avoid drug attrition later in the pipeline by understanding species-specific toxicity. This empowers developers to reduce reliance on in vivo models and improve transition of therapeutics to the clinic.

​Presenter: Dr. Justina Then, CN Bio

Poster 493

Date: Thurs 12 June

Time: 4:30 – 6:00pm

More info

​

A human liver microphysiological system for assessing mechanisms of toxicity

The human Liver MPS enables drug developers to correctly identify DILI and furthermore to capture different mechanisms of toxicity associated with a DILI event that are not typically observed using standard in vitro models. Data-rich analyses from a wide range of clinically relevant biomarkers can be derived and used to make informed decisions to modify drug design and de-risk clinical progression of drug candidates. Together, this enables more efficient drug development and safer medicines in the future.

​Presenter: Dr. Justina Then, CN Bio


Our Team at the MPS World Summit

Atefeh | MPS World Summit

Atefeh

Dr Atefeh Mobasseri, Field Application Scientist at CN Bio, has an extensive background in tissue engineering and regenerative medicine. Before joining CN Bio, she gained a PhD in Biomedical materials from the University of Manchester and carried out postdoctoral roles at the University of Manchester and Kings College London investigating the interaction, and effect, of 3D scaffolds on cellular behaviour. Since joining CN Bio, she has been supporting their European customers in using CN Bio’s range of PhysioMimix® systems to generate high content, human-relevant, data.

adiran

Adrian

A seasoned business developer with extensive commercial experience in the life science sector, Adrian Rea joined CN Bio as the European Director of Sales in June 2022. He brings valuable experience in the 3D cell culture market from his most recent role at InSphero, where he was responsible for developing business opportunities in European and Asian markets. He was previously Sales Director at Enzo Life Sciences, where he managed the restructuring of the global distributor sales channels and expanding the European sales operations. Adrian graduated from the University of Glasgow and received his PhD in pharmacology from Glasgow Caledonian University. 

Oliver | MPS World Summit

Oli

Oliver is a Senior Scientist at CN Bio where his work focuses on modelling MASH in the PhysioMimix MPS system. Oliver completed a BSc (Hons) Biomedical Sciences at University of Manchester and a PhD in Cell Biology at King’s College London, before undertaking postdoctoral work in Bioengineering at Queen Mary University of London. With over 15 years’ experience in academia and industry, Oliver’s background is in Cell and Molecular Biology with a focus on high-content imaging and in vitro assay design.

Yass 2 | MPS World Summit

Yassen

Dr. Yassen Abbas is a Lead Scientist at CN Bio. He completed an MEng in chemical engineering at The University of Edinburgh and joined the European Space Agency as a graduate engineer. He later received a PhD from the University of Cambridge and completed a postdoc fellowship, also at Cambridge on the development of a tissue engineered model of the human endometrium. He has experience with real-time sensor technology, organoids and development of in vitro tissue models using human primary cells. Dr Abbas has published five peer-reviewed scientific articles, four as first author.

Sung BW | MPS World Summit

Sung

A seasoned life science professional with over 20 years of experience in product management, product marketing, and commercial leadership, Sung Lee joined CN Bio as a Director of Product Management in October 2024. He brings valuable experience in the assay kit market from his most recent role at Abcam, where he was the global lead as the senior product director for the Assay Kits and Protein product portfolio. He has held various leadership roles at renowned companies like Abcam (Danaher Company), Epitomics (‘The Rabbit Monoclonal Company’), and Life Technologies (Thermo Fisher Scientific). Sung’s education background includes business certifications from Cambridge Judge Business School and Wharton Business School, and a degree in Molecular and Developmental Biology from the University of California, Santa Cruz.

Justina BW | MPS World Summit

Justina

Justina is a Senior Scientist at CN Bio, focussing on liver toxicology within the R&D team. Her academic foundation includes a PhD in Experimental Medicine and Rheumatology and postdoctoral work at the William Harvey Research Institute (QMUL), where she spent her time investigating the potential of nanotechnology for drug development in rheumatoid arthritis, and synovial fibroblasts. With 9 years in academia and 3 years in industry, she brings a wealth of expertise to advancing biological research and practical applications.

MPS World Summit 2025

Book a meeting at MPS

Speak to our experts

Request a meeting with one of our OOC experts to see how our products and services can support your studies

Request a meeting

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Latest news

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  • CN Bio to participate in 3Rs Collaborative-lead project with FDA to build confidence in Liver MPS for DILI June 25, 2025
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