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Discover the applications


Investigate the validated core application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix Core

cnb1476_physiomimix-core_mark_mocks_system_v2
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Consumables

Multi-chip plates
3D validated cells
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

News

June 28, 2024

How in vitro human Gut/Liver models increase confidence in ADME estimations before human trials 

Imagine a world where developing new medicines is faster, cheaper, and less reliant on the use of animals for testing. Novel multi-organ in vitro

Category iconBlog Tag iconADME,  Bioavailability,  Organ-on-a-chip

June 28, 2024

Organ-on-a-chip adoption: The roadmap to broader use

Paving the way for Organ-on-a-chip adoption Drug discovery is becoming more complex as we move from a small molecule world to large molecules and

Category iconBlog

June 27, 2024

CN Bio appoints Lydia Seymour as VP People and Culture to further strengthen leadership team

Key appointment to support continued UK and US team expansion CN Bio, a leading provider of single- and multi-organ microphysiological systems,

Category iconPress releases Tag iconCN Bio Team,  New Starter

June 13, 2024

Global Fatty Liver Day 2024: How Organ-on-a-Chip Addresses R&D Challenges

To commemorate Global Fatty Liver Day on June 13, this article explores how organ-on-a-chip models are transforming liver disease research. Over

Category iconBlog Tag iconMASLD,  NAFLD,  NASH

June 7, 2024

Meet the CN Bio team -Dr. Dharaminder Singh

Welcome to our new "Meet the team" blog series, where you'll get a behind-the-scenes look at the incredible individuals who make our company

Category iconTeam Q&A,  Blog

April 23, 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10M and $5.5M, respectively. Investment will expand product

Category iconPress releases Tag iconfunding,  investment

April 19, 2024

Understanding the mechanism of toxicity: OOC’s crucial role

It’s commonly acknowledged that the current drug discovery process is inefficient with large numbers of drugs failing in the clinic. Almost a third

Category iconBlog

April 15, 2024

CN Bio selected for NC3R’s SensOoChip Challenge to develop advanced Heart-on-a-Chip

Part of the wider CRACK IT scheme – the multi-challenge competition aims to leverage CN Bio's existing OOC expertise - our MPS development and

Category iconPress releases

January 30, 2024

CN Bio appoints Joseph Parisi as US Director of Sales

CN Bio appoints Joseph Parisi as US Director of Sales to support accelerated growth in key OOC market CN Bio, a leading Organ-on-a-Chip (OOC)

Category iconPress releases

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Latest news

  • Which microphysiological system contexts of use are aligned with regulatory roadmaps? June 2, 2026
  • A new era of drug development: Comparing regulatory roadmaps to reduce animal testing June 2, 2026
  • CN Bio Participating in a New Critical Path Institute Coalition of New Approach Methodologies Developers (NAMs-DC) to Support Advancement in Drug Development May 20, 2026
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