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Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix Core

cnb1476_physiomimix-core_mark_mocks_system_v2
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Consumables

Multi-chip plates
3D validated cells
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the validated core application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

Blog

July 24, 2024

6 Challenges in ADME Drug Development

When developing drugs, we rely heavily on in vitro, in vivo animal and in silico models to predict how the human body will interact with drugs before

Category iconBlog Tag iconADME bioavailability

June 28, 2024

How in vitro human Gut/Liver models increase confidence in ADME estimations before human trials 

Imagine a world where developing new medicines is faster, cheaper, and less reliant on the use of animals for testing. Novel multi-organ in vitro

Category iconBlog Tag iconADME,  Bioavailability,  Organ-on-a-chip

June 28, 2024

Organ-on-a-chip adoption: The roadmap to broader use

Paving the way for Organ-on-a-chip adoption Drug discovery is becoming more complex as we move from a small molecule world to large molecules and

Category iconBlog

June 13, 2024

Global Fatty Liver Day 2024: How Organ-on-a-Chip Addresses R&D Challenges

To commemorate Global Fatty Liver Day on June 13, this article explores how organ-on-a-chip models are transforming liver disease research. Over

Category iconBlog Tag iconMASLD,  NAFLD,  NASH

June 7, 2024

Meet the CN Bio team -Dr. Dharaminder Singh

Welcome to our new "Meet the team" blog series, where you'll get a behind-the-scenes look at the incredible individuals who make our company

Category iconTeam Q&A,  Blog

April 19, 2024

Understanding the mechanism of toxicity: OOC’s crucial role

It’s commonly acknowledged that the current drug discovery process is inefficient with large numbers of drugs failing in the clinic. Almost a third

Category iconBlog

September 5, 2023

A guide to pre-validating primary cells for use in Organ-on-a-chip assays

Mirror, mirror on the wall, which is the best cell of them all? If you are considering incorporating Organ-on-a-chip (OOC) technology into your

Category iconBlog

March 16, 2023

Immune-mediated DILI – Predicting the unpredictable!

Different types of Drug-induced Liver Injury (DILI) Drug-induced liver injury (DILI) is a longstanding and significant problem for clinicians,

Category iconBlog

January 9, 2023

The U.S. FDA Modernization Act 2.0. Now the animal testing mandate is removed, learn what can be embraced in its place.

What is the FDA Modernization Act 2.0, and what does it mean? The U.S. Food and Drug Administration (FDA) are the federal agency tasked with

Category iconBlog

Speak to our experts

Request a meeting with one of our OOC experts to see how our products and services can support your studies

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Latest news

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  • Taking organoids to the next level January 14, 2026
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