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Explore our solutions


PhysioMimix® is a suite of hardware, consumables and assay protocols that enable you to recreate complex human biology and accurately predict human drug responses.

PhysioMimix Core

cnb1476_physiomimix-core_mark_mocks_system_v2
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Consumables

Multi-chip plates
3D validated cells
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Models

Single-organ models
- Liver-on-a-chip model
- Lung-on-a-chip model
Multi-organ models
- Gut/Liver-on-a-chip models

Support packages

PhysioMimix® support packages

Discover the applications


Investigate the validated core application areas that our PhysioMimix® products and services support

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Disease modeling

Metabolic dysfunction-associated steatohepatitis
Hepatitis B
Pulmonary infection
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Safety toxicology

Drug-induced liver injury
Immune-mediated liver injury
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ADME

Drug absorption
Drug metabolism
Drug bioavailability
Oligonucleotide delivery
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Studies as a service


Our team will work collaboratively with you to design a study around your research goals and generate actionable data within weeks

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icon-nash-1-150x150.png MASLD/MASH
icon-dili-tox-150x150.png Drug-induced liver injury
icon-adme-150x150.png ADME

News

June 10, 2025

CN Bio introduces cross-species DILI services to enhance in vitro to in vivo extrapolation during preclinical drug development

CN Bio, a leading provider of Organ-on-a-chip (OOC) systems and solutions that accelerate drug discovery and development workflows, has introduced two

Category iconPress releases

May 20, 2025

CN Bio expands access to OOC solutions for APAC customers with distributor agreement in South Korea

Partnership with SCINCO strengthens international sales and technical support channels in key region as part of ongoing global expansion CN Bio, a

Category iconPress releases

May 1, 2025

Microphysiological systems for mAbs development: how do they address animal limitations?

Welcome to part two of our blog series exploring the FDA’s announcement to phase out the animal testing requirement for monoclonal antibodies (mAbs),

Category iconBlog

May 1, 2025

Why the FDA animal testing phase-out for monoclonal antibodies?

In a groundbreaking press release on April 10th, 2025, the FDA announced its decision to phase out animal testing requirements for monoclonal

Category iconBlog

April 24, 2025

CN Bio and Pharmaron establish long-term strategic partnership to develop OOC technologies on a global R&D platform

CN Bio and Pharmaron partnership to validate and promote the application of CN Bio’s PhysioMimix technology, with future opportunities for novel

Category iconPress releases

April 10, 2025

FDA’s plan to phase out animal testing requirement for monoclonal antibodies and other drugs with more human-relevant methods

Implementation of this new regimen will begin immediately for investigational new drug (IND) applications, where the inclusion of NAMs data is now

Category iconPress releases Tag iconGeneral OOC

February 24, 2025

The Rise of Oligonucleotide Therapeutics: Overcoming ADMET Development Challenges with Human-Centric Approaches

New modality drugs, or advanced oligonucleotide therapeutics, refer to innovative approaches that go beyond traditional small molecule approaches to

Category iconBlog Tag iconADME,  Oligonucleotide delivery

February 4, 2025

CN Bio launches PhysioMimix® DILI assay kit: Human 24

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced

Category iconPress releases

January 13, 2025

CN Bio signs strategic partnership with Primetech Corporation to establish distribution channel for OOC solutions in Japan

Agreement establishes direct distribution channel for customers in Japan, providing local support and expertise. Partnership solidifies CN Bio’s

Category iconPress releases

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Latest news

  • Do MHRA and FDA guidelines on non-animal methods in drug development align? March 27, 2026
  • CN Bio to participate in 3Rs Collaborative-led project with FDA to build confidence in Liver MPS for DILI – now ISTAND accepted! January 25, 2026
  • Taking organoids to the next level January 14, 2026
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